Osteoporosis Prevention

• Most common and mildest type of Osteoporosis.
• Bones predisposed to fracture. Most fractures occur before puberty.
• Normal or near-normal stature.
• Loose jOsteoporosisnts and muscle weakness.
• Sclera (whites of the eyes) usually have a blue, purple, or gray tint.
• Triangular face.
• Tendency toward spinal curvature.
• Bone deformity absent or minimal.
• Brittle teeth possible.
• Hearing loss possible, often beginning in early 20s or 30s.
• Collagen structure is normal, but the amount is less than normal.

• Most severe form.
• Frequently lethal at or shortly after birth, often due to respiratory problems. In recent years, some people with Type II have lived into young adulthood.
• Numerous fractures and severe bone deformity.
• Small stature with underdeveloped lungs.
• Collagen improperly formed.

• Bones fracture easily. Fractures often present at birth, and x rays may reveal healed fractures that occurred before birth.
• Short stature.
• Sclera have a blue, purple, or gray tint.
• Loose jOsteoporosisnts and poor muscle development in arms and legs.
• Barrel-shaped rib cage.
• Triangular face.
• Spinal curvature.
• Respiratory problems possible.
• Bone deformity, often severe.
• Brittle teeth possible.
• Hearing loss possible.
• Collagen improperly formed.

• Between Type I and Type III in severity.
• Bones fracture easily, most before puberty.
• Shorter than average stature.
• Sclera are white or near-white (i.e., normal in color).
• Mild to moderate bone deformity.
• Tendency toward spinal curvature.
• Barrel-shaped rib cage.
• Triangular face.
• Brittle teeth possible.
• Hearing loss possible.
• Collagen improperly formed.

For a number of years, investigators have been dOsteoporosisng special studies on the appearance of Osteoporosis bone under the microscope. They noticed that some people who are clinically within the Type IV group had a distinct pattern to their bone. When they reviewed the full medical history of these individuals, they found that groups had other features in common. They named these groups Types V and VI Osteoporosis. Patients in these two groups do not have evidence of having mutations in the type I collagen genes.